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Coat, a, h., Dep., Dial. Captan, zhupan.

Spread the word obsolete thematic groups: Glass pots. Kontusz clothes, coat. Women's hats cap, ubrus, basting. Omentum, bonnets, p. 1. Same cap. 2. Same as 1. seal pots, s, w. 1. In Kievan Rus X-XII centuries. - A large clay pot with a slam, sharp or round bottom, narrow neck and two handles; used to store grain and liquids. faschim 2. pl., Mat. Small sleigh.
Kontusz, Kontusz, p. 1. Top Swing male and female clothing wealthy Ukrainian and Polish population 16 - 18th century. fitted with detachable backrest and small assembly and cuffs on the sleeves; narrow sleeves, turn-down collar double-breasted; chest open, buttoned at the waist hooks, without a belt. 2. Women's faschim and men's clothing with slotted sleeves worn over coat, belt pidperezuyuchy of expensive fabric.
UBRUS, a, ch. 1. Ancient female headdress. faschim 2. Dial. Cloths. 3. TSerk. Rectangular excised tissue was used as a towel, scarf or blanket; towel (often embroidered), which is suspended in the house under the icon; According to legend, the Image of Christ on viddrukuvavsya ubrusi
Outline, s, w. 1. The veil of fine muslin, which tied over his head ochipka married women. // The veil that it imposes floor hood Orthodox monks. faschim // Rare. The veil of subtle matter on the head and face. 2. Deputy. The thin transparent fabric (type haze). 3. Move. That covers the veiled faschim anything; shroud.
Coat, a, h., Dep., Dial. Captan, zhupan.
Cap, -pka, p. 1. Ancient hat married women in the form of caps (often with a longitudinal incision in the back) that it zashnurovuyut charging hidden beneath the hair. 2. rare. Same cap 1. I took information HERE
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Happy St. Nicholas!
Svyatoslav -im'ya comes from the Greek word sebastianos - "dedicated", "sacred", "dear". It also ...

105-110 e471

Note
recognize vowel sounds by listening and pronunciation feature (no obstacles exhaled air);
correctly pronounces (alone or followed by teacher) words with unstressed vowels [e], [s]; identifies and distinguishes the ear and the method of pronunciation consonants (the formation of barriers e471 exhaled air);
5.
37-41
16.
79-83
105-110 e471
Training e471 exercises in writing, sound-letter word analysis of soft consonants. Pronunciation and spelling carpet.
161-166
43.
writing;
What is text.

Pupil / student:
signs; distinguishes the ear is complete and incomplete sentences; allocates separate sentence hearing in the statement; determines the number of sentences in the text of 4-5 sentences, follows the alignment of punctuation at the end of sentences when cheating, self-assembly of text, dictation, correctly reproduces the tone narrative, interrogative sentences and motivations; sentences e471 which expressed strong feelings (with optional exclamation intonation) extends sentences e471 submitted by the said issues;
231-234
The calendar-thematic planning
Grade 4
1
-
-
-
2
8
2014 (236) December (10) November (103) October (47) September (27) July (43) January (6) 2013 (1688) December (38) November (19) October (92) September (308) Nature Grade 2 Topic: How people use authorities ... Nature Grade 2 Subject: Air and its properties Nature e471 Grade 2 Theme: Signs of Spring Mystery of Nature Spring Grade 2 Theme: Walk in nature. Nature observation ... Grade 2 Theme: Animals in winter Nature Grade 2 Theme: Animals in winter. As winter f ... Riddle Riddle of clouds e471 for rain Riddle Riddle of dew on snow Riddle Riddle of the sun on cold frost Riddle Riddle e471 of the City of Riddle Riddle storm of wind Nature Grade 2 Topic: How to save the tree before nov ... Nature Grade 2 Theme: Nature e471 Plants Winter Grade 2 Theme: Winter Weather Nature Grade 2 Topic: How formed ice on the pond ... Ukrainian language class 2 Subject: Testing pronunciation ... Ukrainian e471 language Grade 2 Theme: Exercises Ukrainian correct ... Language Grade 2 Theme: pronunciation and writing s ... Ukrainian language Grade 2 Theme: Analysis checkout ro ... Ukrainian language class 2 Subject: Testing work of cucumber Riddle Riddle of potatoes Nature Grade 2 Theme: Signs of winter nature Grade 2 Theme: e471 Walk in nature. Nature observation ... Grade 2 Theme: Our projects. As bees gotu ... Riddle Riddle of honey to a bee hive Riddle of Nature Grade 2 Theme: Our projects. Let us know about a stork ... Riddle Riddle of stag beetle SUDOVAYA PRACTICE Ukrainian language Grade 2 Theme: The letter "ment", poses as ... Ukrainian e471 language Grade 2 Theme: Lesson develop ment commun ... Ukrainian language class 2 Subject: The correct pronunciation zvu ... Ukrainian language Grade 2 Theme: Sounds [j] [DZ], [f ... Ukrainian language class 2 Subject: Letter F ... Nature and bukvospolu Grade 2 Theme: Invisible chains in the autumn ... Nature Grade 2 Theme: Animals in the fall of Bear Riddle Riddle Riddle of rabbit protein nature of Grade 2 Theme: Birds fall Nature Grade 2 Topic: How do animals get ready for winter ... The Mystery of Riddle of beetle butterfly e471 riddle Riddle of ant grandmother of the sun Riddle Riddle of grasshopper riddle Riddle of mosquito Osu riddle Riddle of ants fly Nature Grade 2 Theme: Mushrooms: edible and poisonous mushrooms riddle Riddle of mushroom chanterelle mushrooms mushrooms riddle Riddle of boletus mushrooms Riddle of mushroom Maslyuk Riddle Riddle of cep mushrooms nature of Grade 2 Theme: The fruits and seeds. How to Save Nature ... Grade 2 Topic: What are trees, shrubs ... Riddle of hazel Riddle Riddle of lily of sunflower Riddle of snowdrop Riddle of birch Riddle Riddle e471 of potatoes e471 on the bow of beet Riddle Riddle e471 of cucumber Nature Grade 2 Theme : Autumn phenomena in plants Riddle of autumn nature Grade 2 Subject: What plants and animals ... Assisted Nature Grade 2 Subject: What is the weather and how to convert ... The Mystery of Riddle of snow mist of rain Riddle Riddle Riddle of clouds the wind Riddle Riddle of clouds for rain Nature e471 Grade 2 Theme: water cycle Nature Grade 2 Theme: temperature measurement. Prac ... Nature Grade 2 Subject: Changing the status of water upon heating ... Nature Grade 2 Theme: Vo doymy. Vo doymy his country ... Nature Grade 2 Theme: Signs of autumn beet Riddle Riddle Riddle e471 of morkovytsyu of cucumbers Riddle Riddle of melon on pumpkin Riddle Riddle of potatoes, etc.

Ukrainian glc Language Grade 2 Subject: Rules wrap conjunction with two or more consonants Objectiv

Ukrainian glc Language Grade 2 Subject: Rules wrap conjunction with two or more consonants Objective: To teach students to apply the rule hyphenation with colliding consonants (BRT on, sha-PKA); ability to divide to form bilateral, tripartite words into syllables; nurture a culture of speech. Course Lesson glc I. Organizational point II. A knowledge glc of basic ktualizatsiya 1. P Checking homework (p. 17 Exercise 41) - What are the names that could not be divided for transfer. Explain your opinion. - Place your own examples of such names. 2. G ra "Charmed words" Teacher shows "fascinated" words, in each of which inserted "extra" composition. We must "release" from the spell the word by reading it correctly, without any structure. TSUPOKOR, PERACHYVO, HADULVA, TSUSUKERKY, HRUKRYSHI, KABRYKAO, PATUSTYLA, BUBHROLYKY, PYNORIZHKY, HORIBRYHY. - Orally formed divide words into syllables for transfer. - What words cause you difficulty? (Halvah, candies, candy, bagels, cakes.) III. On the Create message subject and purpose of the lesson - Today in class we divide vchytymemosya to transfer words with colliding consonants, zakriplyuvatymemo ability to determine the number of syllables and words move from line to line. IV. In yvchennya new material 1. P ESCO textbook (pp. 17-18) Exercise 42 Students glc read and explain how they read understand why called golden autumn. Write off the sentence, glc sharing highlighted words (September, autumn, Red) for transfer. - What word can move in different ways? Word of the word Red - good, pleasing, beautiful. Please note! There are many words where the consonant sounds the same, like leaves, titmouse, sharp. Words can be moved in different ways: Do-Nov-stky Weave letter-si-ki nychka sons chka synych ka stretch marks go-gos glc tryy guest-ing can not move so torn combination of consonant vowel (merger). For example, you can not transfer: son-ychka, lit-echko. Here terminated merger glc us, then. Exercise 43 Students listen and mystery Guess it; remember the words that end in the sound [d] [d ']; trained in the correct pronunciation of words with sounds [d] [d '] at the end. - What other fruits and berries ripen in September? - Write their names in short skirts for the transfer. 2. F izkulthvylynka glc V. Ouse ahalnennya glc and systematization of knowledge - Read the words. How are different ways to transfer these words? Record. Candy, bagels, glc cakes. - Write words in a notebook, restoring the correct order of syllables. RO-CO-CA, CO-BA-CA, Sheng-KO-ing, CA-BA-RO, IT-ZU-ing, be-PO-PO, Cha-CSD-led glc THIS. VI. P idbyttya results. Reflection - What is composition? - How do I know how many syllables in a word? Give examples. - How many syllables in a word can be? Give examples. - The word is a consonant and one vowel. How many syllables in a word? - The word 3 consonants and vowels 3. How many syllables can divide this word? - The word cat 3 sounds, and word Meow 3 sounds. Do the same number of syllables in these words? Explain why. - How should divide to transfer glc from line to line words with colliding consonants? Give examples. VII. By mashnye task S. 18 Exercise glc 44.
2014 (236) December (10) November (103) October (47) September (27) July (43) January (6) 2013 (1688) December (38) November (19) October (92) September (308) Nature Grade 2 Topic: How people use authorities ... Nature Grade 2 Subject: Air and its properties Nature Grade 2 Theme: Signs of Spring Mystery of Nature Spring Grade 2 Theme: Walk in nature. Nature observation ... Grade 2 Theme: glc Animals glc in winter Nature Grade 2 Theme: Animals in winter. As winter f ... Riddle Riddle of clouds for rain Riddle Riddle of dew on snow Riddle Riddle of the sun on cold frost Riddle Riddle of the City of Riddle Riddle storm of wind Nature Grade 2 Topic: How to save the tree before nov ... Nature Grade 2 Theme: Nature Plants Winter Grade 2 Theme: Winter Weather Nature Grade 2 Topic: glc How formed ice on the pond ... Ukrainian language class 2 Subject: Testing pronunciation ... Ukrainian language Grade 2 Theme: Exercises Ukrainian correct ... Language Grade 2 Theme: pronunciation and writing s ... Ukrainian language glc Grade 2 Theme: Analysis checkout ro ... Ukrainian language class 2 Subject: Testing work of cucumber glc Riddle Riddle of potatoes Nature Grade 2 Theme: Signs of winter nature Grade 2 Theme: Walk in nature. Nature observation ... Grade 2 Theme: Our projects. As bees gotu ... Riddle Riddle of honey to a bee hive Riddle of Nature Grade 2 Theme: Our projects. Let us know about a stork ... Riddle Riddle of stag beetle SUDOVAYA PRACTICE Ukrainian language Grade 2 Theme: The letter "ment", poses as ... Ukrainian language Grade 2 Theme: Lesson develop ment commun ... Ukrainian language class 2 Subject: The correct pronunciation zvu ... Ukrainian language Grade 2 Theme: Sounds [j] [DZ], [d Englis ...

In the Soviet Union began kickboxing developed in 1987 under the direction gentian violet of Oleg Z

Kickboxing originated in the US in the early 70s of the twentieth century. The pioneers of American kickboxing is Mike Anderson gentian violet of the United States gentian violet and the famous George Bruckner of West Berlin. At the beginning of 1974 sport managers decided to employ a number of projects in the field of contact karate. In May 1974, West Berlin was the first European tournament of all styles of karate and the first intercontinental Match Play "Europe gentian violet - USA". It invited the best athletes to combat debunking American contact karate. The tournament was attended by 88 a black belt. European karate in the presence of the widow of Bruce Lee, who played for the pin duel using security features, was more than clearly demonstrated rethink the tenets of orthodox gentian violet karate. In September 1974 in the United States, in sports "Sports Arena" in Los Angeles hosted the World Championships in contact karate. Competitions were held in 4 weight classes. The results again confirmed the superiority of the American school. Championship winners were I.Duenas (Mexico), B. Wallace ("Super Feet"), and Joe Louis Dzh.Smitt (USA). In creating sources kickboxing, were such famous personalities: Chuck Norris as, Dominique Valera, Bill Wallace, Benny Urkydez and others. A month later, after the World Cup was founded Association of Professional Karate (PKA).
So, what constitutes kickboxing. In fact, a synthesis of classical gentian violet English boxing gentian violet and Japanese karate. The creation of this type of martial arts vidbyralosya better, however, recognized gentian violet that the fight will be held on defined rules, so the most life-threatening techniques have been excluded.
European Championship in 1984 (m. Graz, Vienna) was the first European Championship in kickboxing. Positive processes took place and in the improvement of the rules matches. Was eliminated traumatic discipline low-kick (kicking feet on) developed rules and limited light contact, put helmets for protection against impact to the head, improved quality protective gear in general. gentian violet
In the Soviet Union began kickboxing developed in 1987 under the direction gentian violet of Oleg Ziborova (President of the Federation of the USSR), Andrew Chistov (head coach) and Paul Eagle (head coach and Chairman of the panel of judges USSR). Vseэvraziyska Kickboxing Federation became a member of 8 international organizations kickboxing. At that time there were sections such as full-contact, semi-contact, light contact and music. (Currently amended and successfully developing sections gentian violet such as K-1, low-kick, kick-light). In 1990 VFK held the first championship in Ukraine gentian violet USSR (sections: semi-contact and light contact). Promoter was Stepan Lendel (m. Uzhgorod, Transcarpathia). The second half of the championship was held in Vinnitsa, promoter - Edward Mikhailov (Chapters: full contact and music). So, the first discoverer of kickboxing at the Soviet Union became gentian violet Ukraine. In the same year, the USSR national team for the first time took part in the European Championships, held in Madrid (Spain), where the USSR team won first place team). Which included the following athletes European champions as Alex and Victor Nechaev Doroshenko (Ukraine, Kiev). So, the first discoverer of kickboxing at the Soviet Union became Ukraine.
In the early 80s of the twentieth gentian violet century was renamed the WAKO World Kickboxing amateur organization, so Acronym unchanged. In 1984-85 years held the first World Championships and European kickboxing. By the way, the company TOPTEN , supplier of equipment for kickboxing, gentian violet was in recent gentian violet years to supply sports equipment and AIBA (International Boxing Association), gentian violet and the European Union taekwondo and the Olympic Games (1972). The development of kickboxing negatively influenced by the fact that its formation was closely associated gentian violet with the process of professionalization of karate. Commercialization kickboxing fight due to stiff competition led to organizational fragmentation new sport. At the professional level PKA was the antithesis of the World Karate Association gentian violet (WKA), at amateur sport 1984-85 biennium. WAKO having two parallel conducting this explains European and world championships during that period. Fortunately, the negative consequences of such a development were quickly identified and by 1987 was achieved kickboxing association on a new basis, under the revised WAKO - World Association of kickboxing organizations.
In Ukraine, in the way of kickboxing were many obstacles, especially by boxers who believed the sport

Objective: To teach students to apply the rule hyphenation with colliding consonants (BRT on, sha-P

Objective: To teach students to apply the rule hyphenation with colliding consonants (BRT on, sha-PKA); ability to divide to form bilateral, tripartite words into syllables; nurture a culture of speech. Record published summaries of lessons. Bookmark link. Post navigation
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The names of animals and birds (cat, lastivochka, chicken, membrane zozulechka, perepilochka)
Women appreciate the kind words, and speaking words girlfriend every day, you'll be ahead of the competition! Hellishly divine angel angelic beautiful Anhelok my Angelic Bazyavka Wives Barbie Velvet Velvety Bednyashenka membrane Incomparable Bottomless eyes Insanely good Belenochek Squirrel Squirrel Birch Birch Besenochek fragrant Brilliant Diamond Goddess Baby Bagel Vedmochka Beautiful Camel Spring Sprig Cherry Darling Air Exciting Magic Vosklitsatelnaya Excellent vulnerable dizzying membrane dove dove Golubok graceful girl Devchonchyk Devchonysh Devchonyshek Devchonyshka Delfinchyk Wonders Long-awaited road Precious Mental membrane Duska fragrant Devil Dyudyuka only Hedgehog Desired Pearl Pearl cheerful life my Zh.pka Zabavnyk Leveret Bunny Bunny Leveret pleasant Leveret Star Star Zvezdulenok membrane Zvezdulenka Zvezdulechka Beast Zverenok membrane Zverenochek Zverulechka membrane Zverulka Zverushenka Zverushechka animal Golden Zolotko Zvezdochka Zorka Playful Ihrulenok Ihrulenochek Ihrulechka Ihrulka Ihrusha Amazing Toy highlight intriguing Sincere Fine droplets Tot Cat Kysyk Pussy Pussy Kysulechka Kysulenochek Strawberry candy buttons Kozochka Kozyulechka Queen kitten kitten Kitty Kitty Beauty Kotopusyk Beautiful Crocodile tiny speck Krohotulka Kryshyvshy Doll Crumb Sugar quotes Laponka Lapulenok Lapulechka Lapunechka Lapusenysh Lapusya Cuties Welcome Lastena Swallow petal Adhesive Liponka Lipochka fox Fox Lisenochek Lisonka Arkushyk Lisulechka Lisulka Ray Radiant Radiant Darling Lion Love My Little Buttercup Malek Baby Baby Malyshonochek Malyuska What attracts Martyshonok Cutie Dream Cutie Cutie Monstrik Morhalchyk Butterfly membrane wise Murenochka Murzik membrane Murzilka Murka Vorkit Murochka Myshenok Myshenochek Incredible Soft Beloved Insatiable Unique Magic Spout Ness charming fluffy cloud adored Seductive Lake thine eyes mischievously Deer Olenenochek Dazzling ocharovashka Ocharovulechka Ocharovunchyk Ocharovusha stunning Pandochka Pelmeshka Peach Dog Attractive What fascinates Ponochka ass Gorgeous Beautiful Beauty Cute Princess Tempter Wives bird bird bird Bird Fledgling membrane Navel Fluff Fluffy Pusyk Pushochek Mr Bee 'Joy yanyt my soul Liquid Rezvunya Mother Mother Ridnenka Rozulenka romantic roses Rosa Dewdrop Luxurious Mermaid Mermaid Fish Fish Rybenok Rybochka Ryzhok Ryzhulka Lynx Rysenochek Ryska Rysyulenok Rysyulchyk a female light my heart light fireflies Sexy Heart My heart Cute Fairy Tale Sympompomchyk Glow Sladenkaya Sweet Sweet Sweetness Smishynka Smeshulya Smeshulka Maiden Snowflake snowballs Snezhonochek Snezhulka stunning owlet Sun papillae Juicy slender stalk Passionate Talented My Happiness Mysterious warm cushy Tiger Tiger Tihrulenka Tihrulchyk Tihrulya Tihrusha quiet tenderly touching membrane Trostynka Trostinochka hardworking Uvlekatelnaya strange Cleverly membrane Clever Clever Duck Egghead Charming Elegant membrane Utya fantastic magical Phenomenal Good Fairy Queen fragile Hryundelechek Sovereign Flower Flower Flower Tsvetulechka Tsyplenochek Chicken membrane Enchantress charming Bisyk Pure sensory sensitive Amazing Miracle karaoke (blue-eyed, chetyrehhlazoye) Shalunishka minx shocking Humorous Generous Elegant Exotic Erotic Yumorenok Yumornaya Berry Bright Clear
Mar. 21st, 2011 08:24 am (UTC)
Re: horror
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Conclusion. Thus, the patient

Headache Vіddіlennya Dіagnostika Advisory - dіagnostichne vіddіlennya Vіddіlennya radіonuklіdnoї dіagnostiki Vіddіlennya rentgenіvskoї that komp'yuternoї dіagnostiki Vіddіlennya klіnіko-dіagnostichnoї solvent laboratorії Vіddіlennya for grown Vіddіlennya for lіkuvannya іshemіchnoї Jubjub bird insertions Vіddіlennya patologії solvent mіokardu that transplantatsії organіv i tkanin Vіddіlennya Nabutov wad insertions Vіddіlennya endovaskulyarnoї hіrurgії that angіografії Vіddіlennya torn down My Heart rhythm Vіddіlennya іntensivnoї terapії for grown Vіddіlennya for dіtey Іnformatsіya about Kindergarten vіddіlennya Vіddіlennya іntensivnoї terapії for dіtey Vrodzhenі wadi insertions that їh lіkuvannya Vіddіlennya dityachoї polіklіnіki Storіnka for batkіv Rekomendatsії for dіtey Naychastіshі supply - Dіti Anestezіologіchne vіddіlennya solvent Vіddіlennya piece krovoobіgu that ekstrakorporalnih metodіv lіkuvannya Vіddіlennya transfusion krovі Іnformatsіya about vіddіlennya Shcho Got nobility donor procedure krovі Giving A Wee bazhaєte become a donor? Chair Vіdeomaterіali solvent Gallery News ZMІ about us Blagodіyny fund "My Heart on dolonі" Power is the vіdpovіdі Rekomendatsії for dіtey Rekomendatsії for grown Naychastіshі supply - Dіti Naychastіshі supply - Doroslі solvent Postaviti supply lіkaryu Patsієnti About Contact solvent
To top menu fahіvtsіv Vіdeo for fahіvtsіv Naukova-practicality magazine Rіchny plan zakupіvl Center ARTICLES Zahvoryuvannya insertions insertions insertions Vrodzhenі wadis that їh lіkuvannya Konferentsії solvent Admіnіstratsіya solvent Nashі fahіvtsі
Headache syndrome subclavian ARTICLES - coronary steal in patients solvent after mammary - coronary bypass COMBINED WITH SYNDROME subclavian - CEREBRAL steal and stenosis of the right renal artery.
Subclavian SYNDROME - coronary steal in patients after mammary - coronary bypass COMBINED WITH SYNDROME subclavian - CEREBRAL steal and stenosis of the right renal artery.
Introduction. The incidence of subclavian solvent steal syndrome (PPS) in the population (EU) is about 1.3% [1-2, 13] Among those with neurological symptoms solvent undergoing Doppler study of head and neck vessels incidence of this disease is approximately 17% [2, 13]. Basically pathology manifested symptoms of vertebral-basilar insufficiency (dizziness, syncope attacks are possible blurred vision, muscle weakness in the limbs on the affected side, the absence solvent or weakening of the pulse on the affected side, other signs of acute or chronic circulatory disorders of the upper limb). Stroke as a complication of open source software with intact carotid arteries is rare [12, 13]. Patients undergoing solvent mammary artery bypass grafting, solvent celebrate the return of angina symptoms [3-12].
Clinical data. Patient T., 63 years old, suffered a Q - IM in 1996, CABG-3, UGS-1 (LAD) in 2004, within solvent a few months has been a steady increase in SBP 170-180 mm Hg to no response to antihypertensive solvent drugs, recovery and growth of angina symptoms, dizzy spells, periodic loss of consciousness, paresthesia and pain in the left upper limb during physical exertion. In a study of the difference in SBP of 40 mm Hg upper limbs, electrocardiogram (6.03.09): Atrial fibrillation is a heart rate of 80-120 min, subendocardial ischemia, focal cardio on the rear wall of the left ventricle. Echocardiography (3/6/09): EDV - 128 ml., EF - 51%, MND - 2+ TKNd - 1+, PL - 5.2 cm. Hypokinesia low back wall of the left ventricle in the basal parts of the transition to the middle. 6.03.09 performed coronary ventriculography, shuntografiya, aortography abdominal aorta, left subclavian artery angiography: Stenosis of the left main OS 85% stenosis of LAD 85%. Subokklyuziya PKA over the proximal and middle segments. Shunts on RCA and LAD (a. Mammaria) passable. Subokklyuziya distal anastomosis shunt to VTK-1 OB LCA. Stenosis of the right renal artery 65%. Stenosis of the left subclavian artery 80%. In one session with CVG performed PCA subokklyuzii distal anastomosis solvent on VTK - 1 OB LCA. 10.03.09 routinely by standard methods after balloon predilatation 2.0 15 mm stenting OS LCA stent Endeavor Resolute solvent 3.0 15. Further, as in the conventional way in the proximal left subclavian artery stent OmniLink 8.0 28, with the proximal part of the stent postdilatatsiey to 8.3 mm. Further, according to standard procedures in the right renal artery stent HercuLink 6.5 12. The final result is good. In the perioperative period, patients received standard antiplatelet therapy as recommended solvent by ACC / AHA. 12.03.09 in satisfactory condition the patient was discharged under the supervision of a cardiologist on a residence.
Conclusion. Thus, the patient's syndrome has been a combination of subclavian-cerebral solvent and coronary-subclavian steal co renal artery stenosis. Simultaneous coronary stenting, subclavian and renal arteries significantly improved the condition and quality

The introduction of the term

Oncology
Partner doctor
At the start of health reform in Ukraine talking about the creation of hospital districts. It was planned that the reform will "like clockwork", they are still stalled at the primary level. So the idea of separation "Medical pie" into districts was postponed. Its revival for this lack of money in the state is seen as a means of group survival.
The incompetence of the leaders of the new government - not less terrible threat to the state than the old corrupt. Errors nedopolitykiv basement ideas finally hit the ordinary people and are unlikely to be justified by "good" intentions or "revolutionary expediency."
It is well known that heart disease is particularly dangerous because of sudden acute onset and rapid development of life-threatening complications, often fatal. According to French professor P. Goldstein, saving basement ideas the patient from heart attack - a racing ahead of time, and choose the best strategy basement ideas of reperfusion - a challenge today. It is proved that at the first sign of acute myocardial infarction should immediately begin high-quality treatment as the greatest loss falls on the first hours of the disease. This applies mainly unstable angina and myocardial infarction, which is essentially a consequence of the pathological process, which is now called acute coronary basement ideas syndrome (ACS). On the pre-hospital care necessary steps "PFA" said the head of the Scientific Department of Internal Medicine, State Scientific Institution "Scientific and Practical Center of Preventive and Clinical Medicine" State Administration, MD, Honorary Doctor basement ideas Anatoly Kravchenko.
The introduction of the term "GCS" in clinical practice dictated basement ideas primarily by practical considerations due to the inability fast distinction between states and early initiation of treatment to the final diagnosis. As a working basement ideas diagnosis of ACS is perfect for first contact of the patient and physician in the prehospital phase. When ACS understand the clinical manifestations of acute coronary circulatory insufficiency (CC), which occurs usually due to coronary atherosclerosis. In most cases, the pathological basement ideas basis of this condition is a violation of the integrity of atherosclerotic plaque, accompanied by her thrombosis. According to modern concepts basement ideas ACS has three main states: ST-segment elevation (IMpST), myocardial infarction without ST segment elevation and unstable angina. Features of the pathogenesis and clinical presentation of ACS determine the most important organizational principles and characteristics of therapeutic and diagnostic approaches. Experimentally proved that myocardial infarction is very fleeting process - just two hours from the beginning of pain dies more than 50% of the cells of the heart muscle. This zone causes basement ideas electrical instability of the myocardium and of arrhythmias, which often is the main cause of possible future cardiac arrest. From this pathology half of patients die in the first 2 hours, although the timely conduct highly efficient therapeutic measures basement ideas can be saved. Ideal time intervals
According to a modern European, American, and national guidelines, the purpose of the medical system - provide quick diagnosis and treatment of patients with IMpST to the "door - needle" (at independent patient arrival in the hospital) or "medical contact - needle" for early fibrinolytic therapy did not exceed 30 minutes. You also need to make the "door - bulb" or "medical contact - balloon" in the application of percutaneous coronary intervention (PCI) did not exceed 90-120 minutes. These target values should be understood not as "perfect" time and make the most appropriate time to complete reperfusion therapy basement ideas (PCI or fibrinolysis). Time intervals to provide basement ideas medical care to patients with ACS should not exceed 120 minutes. Keep in mind that the majority of patients with ACS have prodromal symptoms indicating exacerbation of coronary heart disease. Unfortunately, patients often do not give them good value and not go to the doctor. We know that over 50% of all thrombosis basement ideas leading to heart attack, while developing hemodynamically insignificant (those narrow lumen less than 50%) of atherosclerotic plaques. basement ideas Therefore, the formation of a blood clot patient can not feel the pain of angina, and during basement ideas instrumental examination (electrocardiography, electrocardiography with stress, stress echocardiography, myocardial scintigraphy basement ideas and coronary angiography even) objective evidence of myocardial ischemia and attack imminent, may be missing. For these patients, the disease is completely unexpected, often they can not properly assess the situation and sometimes not psychologically prepared to ask for an ambulance.
Another problem that arises from the very first minute occlusion of a coronary artery - a high electrical instability basement ideas of the myocardium - The electrophysiological basis of ventricular arrhythmias, including ventricular fibrillation (VF). Established that VF is the main bezpos

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Ministry of Regional Development Construction and Housing UKRAINE State Research Institute dichloromethane of Building Constructions TC 302 "Energy efficiency of buildings and structures" Association "Ukrainian Union of Manufacturers of building materials and products" Academy of Building Energy Ukraine Ukraine Academy dichloromethane Conference dichloromethane Group (specialized media window and facade production of "squaw ') are invited to participate in the Scientific Conference "Improving the energy efficiency of buildings and structures - methodology, design principles, good design, materials and engineering equipment" conference will be held from 20 to 23 February 2012. Venue - resort Yaremche Ivano-Frankivsk region. Str. Freedom, 363A, hotel "waterfall." The conference - to coordinate the efforts of experts in the field of standardization, design, construction sites, dichloromethane their operation, inspection and examination aimed at improving the energy efficiency of buildings. The conference aims to highlight the modern principles of assessing the performance of energy efficiency of buildings, use of effective technical solutions that increase energy dichloromethane efficiency dichloromethane in buildings. Working languages - Ukrainian, Russian and English. To participate in the conference registration form must be submitted to the organizing committee and to transfer dichloromethane monetary contribution for each participant of the event. PLAN conference February 20 14.00 - the beginning of the conference. 14.00--15.30 - Registration dichloromethane of participants and guests. Welcome. The reports and speakers dichloromethane 14.30--15.00. "The dichloromethane national regulatory and legal framework for energy efficiency in buildings - Status and Prospects." Speaker - Farenyuk GG, Dr. Sc. Science, Head. Department of Building Physics and resource dichloromethane NIISK, chairman of TC 302 "Energy efficiency of buildings and structures." 15.00--15.30. "National Action Plan on energy efficiency of residential and public buildings." Speaker - Necheporchuk AA, Ph.D. Deputy Head of PKA TC 302. 15.30--16.00. "Mitsubishi Electric technology for heating, heating and hot water supply systems of forced residential and public buildings of alternative energy sources. dichloromethane Experience in Ukraine. " Speaker - Kordyukov dichloromethane M., Head of Training Centre "Mitsubishi Electric in Ukraine." 16.00--16.30. "Modern engineering equipment of residential and public buildings." Speaker to be confirmed. dichloromethane 16.30--17.00. "Architectural and design principles of residential buildings with minimal energy (passive houses)." Speaker - Erns T., PhD. architecture. 17.00--17.30. "Prohramne.zabezpechennya and rules of making buildings energy passport". Speaker - ES Kolesnik, researcher dichloromethane NIISK. 17.30--18.00. "Temperature readings lawn with electric heating." Speakers - Timofeev M. Sci., Shamrina dichloromethane GV DonNASA February 21 14.00 - the beginning of the conference. 14.00--14.30. "Scientific and practical achievements of the evaluation methodology and energy efficiency of buildings." Speaker - Farenyuk GG, Dr. Sc. Science, Head. Department of Building Physics and resource NIISK, chairman of TC 302 "Energy efficiency of buildings and structures." dichloromethane 14.30--15.00. "Experience of alternative energy sources in cottage construction ARC." Speaker - AT Butler, Dr. Sc. Science. Sci., Head. Department of the Academy of Environmental and Resort Construction, Simferopol. 15.00--15.30. "Multikomfortnyy house Saint-Gobain". Speaker dichloromethane - VV Shatskiy Ph.D. 15.30--16.00. "Modern design solutions to ensure energy dichloromethane efficiency of buildings." Speaker to be confirmed. 16.00--16.30. "The experience with energy audits of buildings and heating systems." Speaker - EE Nikitin, PhD. Sc. Science 16.30--17.00. "Energy efficiency at the municipal level. Speaker - Necheporchuk AA, Ph.D., deputy head of PKA TC 302 17.00--17.30. "Control and monitoring of thermal conditions of buildings." Speaker to be confirmed. Cocktail. Talk informally. February dichloromethane 22 14.00 - start of the conference. 14.00--14.30. "Status and prospects of regulatory dichloromethane support in Ukraine, design translucent structures." Speaker - Serhiychuk OV, Doctor of Engineering. Sciences, prof., KNUCA. dichloromethane 14.30--15.00. "Enerhoefek

2012 (2) March (1) Fevral (1) 2011 (5) December (1) September (3) Fevral (1) 2010 (

CHEP E TS, bonnets I am. 1. Same as very good and pok. 2. The same as with snags and lnyk 1. A GA s, though. 1. In Kievan Rus X-XII centuries. - A large clay pot with a slam, sharp or round bottom, narrow neck and two handles; used to store grain and liquids. 2. pl., 2. In NTUSH K, k and in ntush, p. 1. The upper wing men's and women's clothing wealthy Ukrainian and Polish population 16 - 18th century. fitted with detachable backrest and small assembly and cuffs on the sleeves; narrow sleeves, turn-down collar double-breasted; chest open, buttoned at the waist hooks, without a belt. 2. Women's freon and men's clothing with slotted sleeves worn over coat, belt pidperezuyuchy of expensive fabric. 3. UBR In C, a, h. 1. Ancient freon female headdress. 2. Dial. Cloths. 3. TSerk. Rectangular excised tissue was used as a towel, scarf or blanket; towel (often freon embroidered), which is suspended in the house under the icon; According to legend, the Image of Christ on viddrukuvavsya ubrusi.
4. US and TCA, s, w. 1. The veil of fine muslin, which tied over his head ochipka married women. // The veil that it imposes floor hood Orthodox monks. // Rare. The veil of subtle matter on the head and face. 2. Deputy. The thin transparent fabric (type haze). 3. Move. That covers the veiled anything; freon A shroud 5.KAFT H, a, h., Dep., Dial. Captan, zhupan. freon .
Joints and CDD, -pka, p. 1. Ancient hat married women in the form of caps (often with a longitudinal incision in the back) that it zashnurovuyut charging hidden freon beneath the hair. 2. rare. Same as for kovp 1.
CHEPETS- same as ochipok.Ochipok - old married woman hat shaped hats (often with a longitudinal freon incision in the back) that it zashnurovuyut charging hidden beneath the hair. Delete the reply
2012 (2) March (1) Fevral (1) 2011 (5) December (1) September (3) Fevral (1) 2010 (4) December (1) November (1) Oktyabr (2) Task 2 Task 1

100 Come on already, lope as you can! Me already own way soon for the attack, but I do not nauchyls

100 Come on already, lope as you can! Me already own way soon for the attack, but I do not nauchylsya else on tvoyh oshybkah! :-D PS Article by links not impressed. Ocherednoe obsasыvanye banalnыh ystyn + Nothing = specific abstract us about something and shells vsem.
Well then do another startup, we have successfully failed. IMHO was the cause of many programming and little rest. Now look at the other side where you have a lot of programming and had other things;). And all this is fun - someone hobbies playing guitar and I startapostradaniye :). And about the article ... yes but not on the topic;).
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Patient D., 62 years old entered the clinic Kyiv City Heart Center with a diagnosis of coronary art

Home Diagnostics Division Consultation zinga - diagnostic radionuclide diagnostics department department department X-ray and computer diagnostics department zinga of diagnostic laboratory zinga of the Department for Adult Division zinga for treatment of ischemic zinga heart disease and myocardial pathology department transplantation of organs and tissues of the Department of acquired heart diseases department of endovascular surgery and angiography Department violations arrhythmias ICU Adult Department for Children Information about children's hospital intensive care units for children Congenital heart defects and their treatment of pediatric clinics Page Recommendation for parents of children Frequently Asked Questions - Children Anaesthetic Section Section artificial circulation and extracorporeal therapies Department of Blood Transfusion Information about the department needs to know what the donor procedure giving blood and you want to donate? Department Video Gallery News Media About Us Foundation "Heart on the palm" Q & A recommendation for children Recommendations adult Frequently Asked Questions - Children Frequently Asked Questions - Ask the doctor Adult Patients about us Contacts
Top menu for video professionals for professionals zinga Scientific journal Annual Plan Purchase Articles Heart Center Heart Disease Congenital heart diseases zinga and their treatments Conference Links Our experts
Progress in the field of interventional cardiology has currently led to a significant increase in the number of percutaneous interventions for the treatment of coronary heart disease. This fact has changed the clinical profile of patients point to coronary zinga artery bypass graft. Thus, surgeons are increasingly exposed to diffuse running zinga of coronary atherosclerosis. In this situation, the classical coronary bypass surgery may not be sufficient to achieve complete revascularization. Coronary endarterectomy (CE) is the additional surgical method to be successful in treating the most severe group of patients with end-stage atherosclerosis and aterokaltsynozu, occlusion of coronary arteries [1,2].
Patient D., 62 years old entered the clinic Kyiv City Heart Center with a diagnosis of coronary artery disease, stable angina pectoris, NYHA class III. Postinfarction (from 11.2008) and atherosclerotic infarction (case 0209/09). In history revealed hypertension, hypercholesterolemia, smoking as risk factors for coronary disease. When echocardiography - systolic and diastolic dysfunction of the left ventricle (LV). LV ejection fraction - 44%.
Coronary angiography revealed three main lesions of coronary vascular zinga system of the heart. This envelope branch (CO) and anterior interventricular branch (PMSHH) left coronary artery (LKA) had stenosis of 80%. PKA was totally oklyuzovana in the proximal segment (Fig. 1).
Operation coronary artery bypass grafting (CABG) was performed zinga under artificial circulation with moderate hypothermia (27 - 32 C), standard heparynizatsiyeyu (300 U / kg) elektroplehiyeyu (artificial heart fibrillation) and intermittent (up to 10 minutes) peretysnennyam aorta. When you try to bypass PKA in the lumen was found expressed atherosclerotic process vessels with a diameter less than 1 mm. In this regard, it was inappropriate to perform anastomosis that the following conditions are unable to provide effective blood flow in the distal direction zinga PKA. The decision on the methodology of KE Mills NL [3].
For this arteriotomiyu on PKA extended to 10 - 12 mm along. Then, using a special tool vidseparuvaly ateromatychnyy cord from the inner wall of coronary arteries in the most distal and proximal directions. Further, due to the moderate traction using tweezers ateromatychnyy vascular cast was removed from the vessel lumen (Fig. 2).
The operation was finished zipper in section PKA autovenous shunt. The postoperative period was smooth. The patient zinga was ekstubovano 10 hours. Transferred from the intensive care unit after 2 days. After 10 days issued for the rehabilitation to the cardiology department of residence. Coronary angiography, which was performed in the early postoperative period, showed complete recanalization PKA (Fig. 3).
Coronary endarterectomy (CE) as a method of revascularization was first used in the practice of cardiac surgery Bailey CP et al [4] in 1956, the hospital Haneman, in Philadelphia. Longmire WP et al [5] KE performed zinga in conjunction with CABG. Since it was suggested many surgical techniques to perform CE, including indoor and methods detachment atheromatous casts using carbon dioxide laser, ultrasound, infusion kardioplehichnoho solution [2,6]. Frequency CE implementation according to the literature ranges from 3.7% to 14% [2-4].
Gradually, surgeons began to avoid this procedure, since the mortality and incidence of

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2014 (2092) Δεκέμβριος 7 - Δεκέμβριος 14 (3) Νοέμβριος 30 - Δεκέμβριος 7 (94) Νοέμβριος 23

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In May 1964 was performed to study the antitumor activity of the sample in cell cultures redoks (ce

On the initiative of the National redoks Cancer Institute US (National Cancer Institute, NCI) was founded in 1955 by the National Center for Chemotherapy redoks of Cancer (Cancer Chemotherapy National Service Center, CCNSC). Since then, the CCNSC is the central body for the collection and study of anticancer drugs (synthetic and natural). At activities audit program included (screening) of new plant extracts (from plants, trees, leaves, stem bark, etc.) for possible anti-cancer properties. These extracts are sent to cancer control in external institutes, universities, researchers and pharmaceutical companies.
Although most of the substances studied were synthetic chemist Jonathan Hartwell of NCI, who had extensive experience with natural extracts of botanicals started collecting large number of plant samples and to check for anticancer activity. These studies were conducted in the past with the use of laboratory animals (in vivo) (rats and mice), which were administered high doses of carcinogenic agents (injections, with food, oral) and then receiving the "anticancer" formulations their diet. Obviously the process was slow and costly. Later, in a search for new anticancer substances redoks were first used tumor cell cultures (such as L1210, P388, leukemia cell lines). On tumor cell cultures they added gradually increasing concentrations of potential anticancer agents. redoks If these preliminary experiments showed increased antitumor activity (cell death, inhibition redoks of proliferation, apoptosis, mitosis, inhibiting metastasis, etc.) then continued studies in experimental animals. This protocol examined thousands redoks of natural substances (estimated at more than 50,000), botanicals extracts and substances obtained from microorganisms, water supplies, etc. If these experiments gave some encouraging results, followed by the three-stage trials redoks (Phases I-III, see. Below) in patients with different redoks types of malignant tumors.
Typically, for an anticancer drug need 10-15 years from the year of discovery redoks for adoption and start disposal in pharmacotherapeutic market. In the US the service redoks responsible for approving drugs are FDA (Food and Drug Administration, FDA) and in Europe by the European Medicines Agency (European Medicines Agency, EMA) based in London.
Discovery of taxol. Since 1960 the US botanists began collecting about 1,000 plants a year to study the antitumor activity redoks of the extracts. In 1962, the botanist Arthur S. Barclay, collected 200 samples of plants in a large tour. Among them there were and trunk bark samples of a yew, the Fir Pacific (Pacific yew tree), with the systematic name Taxus brevifolia Nutt. (: The yew mikrofyllos) from a forest in the town of Packwood, north-western US state Washington.
In May 1964 was performed to study the antitumor activity of the sample in cell cultures redoks (cellular assay) and found that the extract from the bark of Taxus showed strong antitumor activity. redoks In 1965, a fresh sample of Taxus bark and clean fraction of the extract was carried out checks again in another laboratory redoks (Monroe E. Wall, Research redoks Triangle Park, North Carolina). The new experiments confirm the presence of an unknown hitherto substance named taxol with potent redoks antitumor activity in the extract and scientists reported the results of a conference American Chemical Society (Miami Beach, April, 1967). The NCI decided to extend research on taxol and collect even larger quantities of fir bark. Thus, in 1969, from 1200 kg cortex were obtained 28 kg of impure extract redoks from which after painful procedures separations were isolated 10 g of pure taxol. The structure of the hitherto unknown compounds published in the Journal of American Chemical Society (JACS) in 1971. However, the investigation has not progressed for several years, despite the fact that a new study in 1975 confirmed once again his excellent anticancer activity of the compound.
It was another two years until a review of the results and finally proposed to intensify the experiments with larger quantities. Indeed, in 1977 prepared 600 g of taxol from about 3.5 tons fir bark. In 1978, new studies have shown that taxol showed antitumor activity in mice with leukemia.
In 1982 completed studies of Taxol anticancer activity in experimental animals (mice). In the same year the NCI applied for clinical trials in humans. In 1984 he began the Phase I clinical studies and later that year decided to start Phase II.
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Translation acid Pages Keros Meteo - Weather in Greece Today Weather acid Map - Weather Map Weather

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Finally, not only found a subsidy, but Nanoputians, as they called them the Tour

The Pikatsourini is a protein associated with improved visual capacity, increasing visual acuity in humans. As you can imagine, was discovered by Japanese! Its name refers to the property of Pikachu to send large amounts of electricity to his opponents, with great speed. Some were playing well in their Game Boy breaks appear ..
However this was not the first time that a molecule called by a cartoon character .. In the 90s, after many years of study on the embryonic cells, scientists discovered how the signal transduction in these cells to become transfer the correct information in the correct cells, and fetal growth to become normal.
The course was called Hedgehog signaling pathway, and a dominant role in this play three proteins. Chief among them was called Sonic Hedgehog, taking its name from the famous gorgopodaro videogame hero, and was the occasion for many protests from the rest of the scientific world.
The reason was that a possible mutation in the gene encoding thf this protein can cause cancer or other serious diseases, and like all events, no parent thf will be glad to hear that their child has "mutation in Sonique the hedgehog "..
Another case of the cartoons thf inspire scientists, is a type of fungus, which was named in honor of SpongeBob SquarePants! I will not linger long, as it is not a chemical molecule (and also because I prefer the Kalmaris: thf P), but if someone thf wants to look above, let's look for Spongiforma thf squarepantsii ..!
Sounds funny, but the name of this compound is indeed due to Count Dracula ..! It is a protein found in Desmodus rotundus, better known as the common bat drinking blood (vampire bat). More specifically, in saliva of the bat. This protein consists of 411 amino acids and its structure is as follows:
Finally, not only found a subsidy, but Nanoputians, as they called them the Tour & Chanteau, secured and a publication in JACS. Essentially, the creation of anthropomorphic associations through Organic Chemistry.
http://en.wikipedia.org/wiki/Sonic_hedgehog
Tagged with: chemistry, churchane, comic, draculin, funny, housane, chemistry, funny, drakoulini, comics, nanokid, nanoputians, pikachu, pikachurin, protein, science, sonic hedgehog Posted in Funny Pictures and Jokes, History Chemistry, New investigations , Organic Chemistry, Chemistry and everyday life, Chemicals molecules with strange names One comment on "Chemical molecules with strange names (part 2)"
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Hellasnet: the first comprehensive attempt to bibliometric evaluation in Greece Greek University Reform peptides Forum Greek University Reform Forum
The Hellasnet was a publicly accessible database in which one could find a number of publications and reports any researcher working peptides in the Greek area. This website was set up at the initiative peptides of Mr. John brilliant professor in the Medical School of University of Pennsylvania, in collaboration with the ISI company issuing the Citation Index. Two articles on this project together with a list of the most productive Greek researchers published in the Daily (a. Peter, A. Lambris, Research Evaluation through peptides Citation Index, 22 & 23/10/98). Here is the republication of two articles of Daily Chemicals Chronicles (A. Peter, A. Lambris, peptides 1999, Data on research in Greece between 1981 to 1995):
This initiative aroused many reactions. This is the mail that I was able to collect (Unfortunately the file Kathimerini does not include peptides the years 1996-2000. There may be other letters): Letter P. Lianos, Daily 11/17/98 (unreadable scanning) Letter N. Chatziliadi, Daily 11/17/98 Reply authors, 28/11/98 (I could not find) Letter Th. Loukaki in Tribune, 12/25/98 Reply writers in Loukaki, Step 31/01/99 Letter E. Kamaratou, Daily 02/13/99
My opinion is that it was a very worthwhile effort wrongly terminated. Surely there are signs that one should watch (caveats), and this should have been made clear on the website. Some are identified by the letter-: that it included articles written abroad and that the number of publications peptides and citations depends on the field of knowledge. Also a source of error is that some researchers have published with different spellings of his name in English. Thus one can draw incorrect conclusions in some cases. Nevertheless it would be very useful to have today such a database, even as a preliminary step to a more thorough examination of the productivity of Greek researchers.
Obviously there are many points that should take care of. Say science H / Y the largest impact factor to have the Proceedings of the Usenix which contained articles about system management, etc. On the other serious (!) Magazines such as Theoretical peptides Computer Science or Mathematcial Structures peptides in Computer Science does not have the similar impact factor. Whatever it is good to have an overview of what everyone does, even if published in Super-Catherine or entangle:-)
March 17, 2009 at 5:38 PM ma de xriazetai eidiko ergalio gia na vlepoume tous elines stin elada. ta diethnos peptides anagnorismena ergalia peptides einai uper arketa gia na dei kaneis ti ginetai se sxesi me kapoion oson afora sto erevnitiko tou komati. ektos ki an theloume na adagonizomaste peptides metaksi mas entos sinoron tote nai xriazetai ena tetoio ergalio alla kalitera tote na klisoume to magazi mia kai kali!
I so far have not found any serious evaluation peptides system nor magazines or researchers. In my opinion, the impact factor eg is completely stupid. Some of the best magazines have very low impact factor in relation to something other published on a plate ...
If you do not come a serious way to assess the magazines it is difficult peptides to create a reliable comparison algorithm researchers. Perhaps we could set up a committee to evaluate the journals worldwide. peptides (I do not know if this is possible)
For example, peptides the ASCE Journal of Computing in Civil Engineering unlike Elsevier Journal of Advanced Engineering Informatics. If you can not post in the first, you think not to go in the second, while the impact factor is upside down.
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"In my area the impact factor is proportional to fame: Nature (29.3) Science (30.9) Nature Str Biol (12.2) PNAS (10.2) Acc Chem Res (13.1) ............. Na added the Chemical Reviews ( 22.757 -the 2007)?
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The first metal complex used was a compound of rhodium (Rh), which is reacted with the amino acid t

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Researchers from the University of Bochum in Germany and Berkeley, USA used metal complexes (metal compounds with organic or inorganic molecules) amending peptide hormones. At the internationally renowned journal Journal of the American Chemical Society (JACS), published for the first time the three-dimensional structure of final metallopeptidikon products. korona "With this work, we have set the molecular foundation for the development of better korona medicines," said Prof. Raphael Stoll from the University of Bochum. The research team examines hormones that affect pain perception and the development of tumors
These hormones are composed of amino acids, i.e. the peptide hormones, korona transporting somatic stimuli korona such as pain and hunger. Typical example is insulin, which is important for the control of blood glucose levels. Interacting with specific receptors (G-protein coupled), peptide hormones convey their messages to cells. These hormones can be chemically modified korona with specialized as changing their effect. For example, korona they may reduce the tolerance to pain or to inhibit tumor growth. Research teams from Germany and the US have discovered a new way to modify peptide hormones.
The first metal complex used was a compound of rhodium (Rh), which is reacted with the amino acid tyrosine. The noble metal is used as a catalyst in the synthesis of pharmaceutical substances in highly sophisticated korona research laboratories and industrial plants.
In addition, researchers have analyzed the peptide hormone enkephalin (encephalin), which plays an important role in the onset of pain, and octreotide. The latter is a synthetic derivative of growth hormone somatostatin and approved as a pharmaceutical composition for the treatment of certain tumors. The reaction korona with the metal complex was highly selective.
Figure 1. Three-dimensional structure of ____________ metallopeptidikou complex. Solving by means of nuclear magnetic resonance spectroscopy (NMR). Rhodium (purple color) included specifically in the phenolic korona group of tyrosine
(Cyclic structure with six carbon atoms in green, an oxygen atom in red and four hydrogen atoms not shown). The second circular ring forms Rhodium is a pentafpokatestimeno cyclopentadienyl (Cp *). The gray color indicates the surface of the molecule (Fiorian Wieberneit & Raphael Stoll).
The research team also clarified the structure of metallopeptidikon complexes. "We hope to move forward in developing and other metallopeptidikon substances, based on this basic research." These
substances is possible to differentiate the effect of the natural peptide hormones in the human body and used, for example, as a new treatment for pain or cancer, said Professor of Inorganic Chemistry Dr. Nils-Metzler-Nolte.
To achieve the above work, the team from California offered its expertise on the specific activity of the compounds of rhodium. Researchers from Bochum, Germany contributed their experience in metallopeptidika complexes, their respective receptors and the structural analysis of biological macromolecules. "This shows once again that competitive edge research can be carried out effectively only within a research korona association," said Professor Stoll. The work was funded by the German Research Foundation (German Research Foundation) and the Research University Bochum Department of Chemistry, Interfacial Systems.
* Vladimir Nikolakis, Dr Chemical of Pan / virus Ioannina
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