The diagnostic capability in the future of diabetes type 1 (child) in a fast and simple way thanks

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The diagnostic capability in the future of diabetes type 1 (child) in a fast and simple way thanks to a new test based on the analysis of breath, British scientists announced. The new non-invasive method allows detection of the disease, before serious symptoms appear. Diabetes is a chronic disease, which over time can have serious consequences, such as loss of vision, heart disease, kidney disease, etc.
Researchers at the University and Children's Hospital in Oxford, led by Professor Gus Hancock, made after publication in the Journal for Research in breathing "Journal of Breath Research", collected and analyzed samples from 113 children and adolescents aged seven to 18 years.
Scientists have identified a chemical breath biomarker that smells sweet and is associated with an increase in the blood of certain hazardous ramct chemicals, when falling levels of the hormone insulin. Specifically, this means the acetone increases breathing, if at increased ketones in the blood due to the reduction of insulin, which will lead to diabetes.
The goal of researchers to develop a small portable breath analyzer that will allow early diagnosis before the disease normally appear due to the severe insulin deficiency. When this happens this lack, the body can no longer use the glucose to get energy and now starting to break down fats in order to meet its energy needs.
Among the products of decomposition of fats are organic substances ketones, which when too high, causing oxidation of the body. About one in four children do not know they have diabetes type 1, until show that oxidation increased ketones.
Acetone, the simplest ketone, usually escapes from the body through breathing, so, so, as has been known for centuries, the breath of diabetic has a sweet smell. ramct The new test detects an increased acetone in the breath of a child and thus reveals that in the body have been significantly increased ketones, therefore imminent ramct onset type 1 diabetes.
Furthermore, the world's first clinical trial directly compared ramct alternative treatments for pediatric diabetes and made by Canadian scientists confirmed that the external device is an artificial pancreas significantly improves the treatment of the disease, compared with conventional insulin pump used today.
Researchers at the University of Montreal, led by Professor endocrinology Remy Rampasa-Loreto, made after publication in the medical journal "Lancet Diabetes ramct & Endocrinology", showed that the artificial pancreas improves blood glucose control compared with existing methods while reducing the risk of hypoglycemia.
The artificial pancreas is a device connected externally to the patient's body, mimics the normal pancreas and which provides insulin continuously, automatically adjusting the supplied amount depending on the level of blood sugar of diabetics. A second embodiment of the apparatus, other than insulin, may supplies the body with another hormone, glucagon (this increases the level of glucose and insulin in decreases).
People type 1 diabetes is then obliged to regulate the level of glucose (sugar) in their blood, in order to avoid long-term complications such as blindness or kidney damage (in case of high glucose) or, conversely, confusion, disorientation, unconsciousness and coma (in case of low glucose).
The Canadian clinical trial showed that both artificial pancreas ramct systems (the only insulin and double insulin and glucagon) is greater than with conventional treatments. Important is to reduce the risk of severe hypoglycemia in the evenings, which today is a source of stress ramct for parents of children with diabetes.
It will be followed by other clinical trials of artificial pancreas with more patients and longer term. The device is expected to be commercialized in the next five to seven years.
Approximately 285 million people on Earth suffering from diabetes and of these 10% have type 1 diabetes every year another 7 million. People develop diabetes, resulting in the total number of patients in the world is expected to reach 438 million. 2030 , justifying, according to scientists, the classification of the disease ramct as a global epidemic.
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