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Forget cancer chemotherapy - it's much more effective to spray nano gold rods into the body and heat them up so they toaster cancer cells from the inside. The gold is even no side effect, promising researchers from MIT. By Niels Berg Olsen May 6, 2009 kl. 11:56
The heat is effective as a weapon against cancer cells has long been known, writes Science Daily. The problem has just been that by heating is difficult to avoid damage to healthy tissue adjacent to the tumor.
Geoffrey von Maltzahn says that when treating amide cancer with chemotherapy when 99 percent of the medication did not find cancer cells. But his golden spell that he has received a research award for developing, can bind specifically to cancer cells.
Blood vessels near tumors for the pores, such as nano-rods can penetrate through. The rods are accumulated in the tumor. Radiation in the NIR region (near-infrared) can penetrate the skin cells without damaging them and reach the gold rods, which then heated up to 70 degrees and destroy the cancer cell, they sit in.
Von Maltzahn has developed a polymer coating for gold rods that increases their residence time in the bloodstream significantly. The half-life for their concentration is about 17 hours, which gives them enough time to reach the target. Any excess gold rods flush just out in the urine after a few days the liver and spleen, he said. Documentation
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It sounds like it is a completely new and unexplored territory it here. The Texan (Uni of Rice) researcher - Naomi Halas - have worked in the field for some years. She uses simply Gold nano-shells instead of gold rods. Others amide have worked with carbon nanotubes as similar acts as IR absorbing. The (important) work that remains is to get directed nano-particles into the tumor in sufficient concentration.
"SERS-Coded Gold Nanorods as a Multifunctional Platform for densely Multiplexed Near-Infrared Imaging and Photothermal Heating" in the journal. Advanced Materials, Vol.21, p.1-6, 2009; DOI: 10.1002/adma.200803464
The researchers write (with PEG stands for polyethylene glycol rods are covered with and NR stands for nanorod = nano wand): Based on empirical studies of passive tumor targeting, the enhancement of the PEG-NR circulation hour over reported PEG-nanoshell formulations ska amplify sina passive tumor accumulation in tumors, der, in concert with sin enhanced photothermal heat generation in vitro, would forventes amide Provider overall enhanced photothermal contrast mellan tumor and normal tissue.
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