Radium urea Ra 223 dichloride | CancerConnect News
Newly Diagnosed Center Diagnosing Cancer Introduction to Cancer Treatment Your Cancer urea Treatment Team Optimizing Your Treatment Questions to Ask A Word about Clinical Trials urea Getting a Second Opinion The Role of Caregivers TYPES OF CANCER
Anal Cancer Bladder Cancer Bone Cancer Brain Cancer Breast Cancer Cervical urea Cancer Colon Cancer Esophageal urea Cancer Gastric Cancer Gastrointestinal urea Stromal Tumors Head & Neck Cancer HIV-related Cancers Hodgkin's Lymphoma urea Leukemia Liver Cancer Lung Cancer Melanoma
Mesothelioma urea Multiple Myeloma urea Myelodysplastic Syndrome Myeloproliferative Neoplasms MPN Neuroblastoma Non-Hodgkin's Lymphoma urea Ovarian Cancer Pancreatic Cancer Prostate urea Cancer Rectal Cancer Renal Cancer Retinoblastoma Sarcoma Skin Cancer Testicular Cancer Thyroid Cancer Uterine Cancer Vaginal Cancer CANCER TREATMENT
Introduction urea to Cancer Treatment Clinical Trials urea Chemotherapy Radiation Therapy Surgery Hormonal Therapy Targeted Therapy Stem Cell Transplantation urea Complementary & Alternative Managing Side Effects Support and Resources Provider Directory Drug Dictionary Cancer Dictionary DAILY CANCER NEWS CANCER VIDEO LIBRARY
For urea which conditions is this drug approved? Radium Ra 223 dichloride is indicated for the treatment of patients with castration-resistant urea prostate cancer, symptomatic bone metastases, and no known visceral metastatic disease.
What is the mechanism of action? The active component of radium Ra 223 dichloride is the alpha particle-emitting isotope radium-223 (as radium Ra 223 dichloride), which mimics calcium and forms complexes with the bone mineral hydroxyapatite at areas of increased bone turnover, such as bone metastases The high linear urea energy transfer of alpha emitters (80 keV/micrometer) leads to a high frequency of double-strand DNA breaks in adjacent cells, resulting in an anti-tumor effect on bone metastases. The alpha particle range from radium-223 dichloride is less than 100 micrometers (less than 10 cell diameters), which limits damage urea to the surrounding normal tissue. urea
How is radium Ra 223 dichloride typically urea given (administered)? urea Radium Ra 223 dichloride is administered by slow intravenous injection over 1 minute. Dosage is determined by body weight (50 kBq [1.35 microcurie] per kg body weight) and given at four-week intervals for six injections. Safety and efficacy beyond six injections have not been studied.
How are patients typically monitored? Patients will usually have scheduled urea meetings with their healthcare provider while they are being treated with radium urea Ra 223 dichloride. Typically, blood will be drawn to check levels of blood cells and to monitor functions of some organ systems, such as the kidneys or liver. Patients may also undergo physical examinations, scans or other measures to assess side effects and response to therapy.
In addition, patients will have blood counts measured prior to treatment initiation and before every dose of radium urea Ra 223 dichloride. Physicians are advised to discontinue treatment if hematologic urea values do not recover within six to eights weeks after treatment. Patients with compromised bone marrow reserve should be monitored closely, and radium Ra 223 dichloride urea should be discontinued in patients who experience life-threatening complications despite supportive care measures.
What are the common (occur in 30% or more of patients) side effects of treatment with radium Ra 223 dichloride? Nausea Anemia Lymphocytopenia (insufficient white blood cell counts) Leukopenia (low white blood cell counts) Thrombocytopenia (abnormally low amount of platelets)
What are the less common (occur in 10% to 29% of patients) side effects of treatment with radium Ra 223 dichloride? Diarrhea Vomiting Peripheral edema (swelling of ankles, feet, and legs) Neutropenia (low neutrophil count, a type of white blood cell that helps fight infection) urea
This is not a complete list of side effects. Some patients urea may experience other side effects that are not listed here. Patients urea may wish to discuss with their physician the other less common side effects of this drug, some of which may be serious.
Some side effects may require medical attention. Other side effects do not require medical attention and may go away during treatment. Patients should check with their physician about any side effects that continue or are bothersome.
What can patients urea do to help alleviate or prevent discomfort and side effects? Pay careful attention to the physician s instructions and inform the physician of any side effects. Maintain adequate rest and nutrition. Eat small meals frequently to help alleviate nausea. If patients have been prescribed an anti-nausea medication, they should be sure to take the prescribed doses. Have blood cell count monitored while receiving radium Ra 223 dichloride. urea Drink plenty of fluids. (Patients should ask their physician about the amount urea of liquid to consume
Newly Diagnosed Center Diagnosing Cancer Introduction to Cancer Treatment Your Cancer urea Treatment Team Optimizing Your Treatment Questions to Ask A Word about Clinical Trials urea Getting a Second Opinion The Role of Caregivers TYPES OF CANCER
Anal Cancer Bladder Cancer Bone Cancer Brain Cancer Breast Cancer Cervical urea Cancer Colon Cancer Esophageal urea Cancer Gastric Cancer Gastrointestinal urea Stromal Tumors Head & Neck Cancer HIV-related Cancers Hodgkin's Lymphoma urea Leukemia Liver Cancer Lung Cancer Melanoma
Mesothelioma urea Multiple Myeloma urea Myelodysplastic Syndrome Myeloproliferative Neoplasms MPN Neuroblastoma Non-Hodgkin's Lymphoma urea Ovarian Cancer Pancreatic Cancer Prostate urea Cancer Rectal Cancer Renal Cancer Retinoblastoma Sarcoma Skin Cancer Testicular Cancer Thyroid Cancer Uterine Cancer Vaginal Cancer CANCER TREATMENT
Introduction urea to Cancer Treatment Clinical Trials urea Chemotherapy Radiation Therapy Surgery Hormonal Therapy Targeted Therapy Stem Cell Transplantation urea Complementary & Alternative Managing Side Effects Support and Resources Provider Directory Drug Dictionary Cancer Dictionary DAILY CANCER NEWS CANCER VIDEO LIBRARY
For urea which conditions is this drug approved? Radium Ra 223 dichloride is indicated for the treatment of patients with castration-resistant urea prostate cancer, symptomatic bone metastases, and no known visceral metastatic disease.
What is the mechanism of action? The active component of radium Ra 223 dichloride is the alpha particle-emitting isotope radium-223 (as radium Ra 223 dichloride), which mimics calcium and forms complexes with the bone mineral hydroxyapatite at areas of increased bone turnover, such as bone metastases The high linear urea energy transfer of alpha emitters (80 keV/micrometer) leads to a high frequency of double-strand DNA breaks in adjacent cells, resulting in an anti-tumor effect on bone metastases. The alpha particle range from radium-223 dichloride is less than 100 micrometers (less than 10 cell diameters), which limits damage urea to the surrounding normal tissue. urea
How is radium Ra 223 dichloride typically urea given (administered)? urea Radium Ra 223 dichloride is administered by slow intravenous injection over 1 minute. Dosage is determined by body weight (50 kBq [1.35 microcurie] per kg body weight) and given at four-week intervals for six injections. Safety and efficacy beyond six injections have not been studied.
How are patients typically monitored? Patients will usually have scheduled urea meetings with their healthcare provider while they are being treated with radium urea Ra 223 dichloride. Typically, blood will be drawn to check levels of blood cells and to monitor functions of some organ systems, such as the kidneys or liver. Patients may also undergo physical examinations, scans or other measures to assess side effects and response to therapy.
In addition, patients will have blood counts measured prior to treatment initiation and before every dose of radium urea Ra 223 dichloride. Physicians are advised to discontinue treatment if hematologic urea values do not recover within six to eights weeks after treatment. Patients with compromised bone marrow reserve should be monitored closely, and radium Ra 223 dichloride urea should be discontinued in patients who experience life-threatening complications despite supportive care measures.
What are the common (occur in 30% or more of patients) side effects of treatment with radium Ra 223 dichloride? Nausea Anemia Lymphocytopenia (insufficient white blood cell counts) Leukopenia (low white blood cell counts) Thrombocytopenia (abnormally low amount of platelets)
What are the less common (occur in 10% to 29% of patients) side effects of treatment with radium Ra 223 dichloride? Diarrhea Vomiting Peripheral edema (swelling of ankles, feet, and legs) Neutropenia (low neutrophil count, a type of white blood cell that helps fight infection) urea
This is not a complete list of side effects. Some patients urea may experience other side effects that are not listed here. Patients urea may wish to discuss with their physician the other less common side effects of this drug, some of which may be serious.
Some side effects may require medical attention. Other side effects do not require medical attention and may go away during treatment. Patients should check with their physician about any side effects that continue or are bothersome.
What can patients urea do to help alleviate or prevent discomfort and side effects? Pay careful attention to the physician s instructions and inform the physician of any side effects. Maintain adequate rest and nutrition. Eat small meals frequently to help alleviate nausea. If patients have been prescribed an anti-nausea medication, they should be sure to take the prescribed doses. Have blood cell count monitored while receiving radium Ra 223 dichloride. urea Drink plenty of fluids. (Patients should ask their physician about the amount urea of liquid to consume
No comments:
Post a Comment